The 558-bed Manisa Integrated Health Campus is located on a 97,562 m² site to the east of the city, characterized by an approximately 13-meter elevation difference along the northeast-southwest axis. Responding to the sloping topography, the main Hospital, Polyclinic, and Emergency entrances are organized on different levels to establish a balanced and efficient circulation system throughout the complex.

Polyclinics are located on the ground and first floors of the T1 and T2 Patient Ward Towers, with each examination room positioned to benefit from natural daylight. Diagnostic departments, including Radiology and Nuclear Medicine, are placed on the same levels as the Polyclinics, providing direct and efficient outpatient access.

Patient, visitor, staff, and service flows are differentiated through separate horizontal and vertical circulation zones, minimizing circulation conflicts within the hospital. A separate 1,674-car parking structure, with a total area of 50,220 m², is connected to the hospital at multiple levels.

The hospital program includes 156 polyclinics, 416 patient beds, 89 intensive care beds, 37 neonatal intensive care beds, 10 Labour-Delivery-Recovery units, and 17 operating rooms.